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120507P - ETHICAL ISSUES IN COMMUNITY TRIALS: BENEFITS vs RISKS

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Paper written by Professor Omar Hasan Kasule Sr.


1.0 CHARACTERISTICS OF A COMMUNITY TRIAL
·         A community intervention study targets the whole community and not individuals.
·         For some conditions intervention at the level of the community is more effective in disease prevention that targeting high risk individuals.
·         Intervention at the level of the community may involve environmental changes that are easier to undertake than attempting to produce large scale voluntary behavioral change with regard to disease risk factors.
·         Another advantage of intervention at the community level is that high risk lifestyles and behaviors are influenced more by community norms than by individual preferences.
·         A community intervention has an advantage over other study designs in that it tests the effect of intervention in the actual natural conditions of the community and not in an artificial study situation.
·         It is cheaper and more practical to test interventions at the community level than at the individual level.

2.0 STRENGTHS AND WEAKNESSES
·         The strength of the he community intervention study can evaluate a public health intervention is natural field circumstances.
·         Selection bias is likely to occur when allocation is by community.
·         People in the control community may receive the intervention under study on their own because tight control as occurs in laboratory experimental or animal studies is not possible with humans.

3.0 INFORMED CONSENT
·         The experimental community does not have a chance for individualized informed consent
·         Obtaining individual consent is logistically impossible